Jyotika Bahuguna’s home-page
UniStra tenure track professor
Computational and statistical modeling, basal ganglia, decision making, oscillations…
More info coming soon…
Jyotika’s news and science
How basal ganglia subnetworks tune decision policies to increase reward rate
Adaptive decision-making is not only about choosing the correct option. It also requires choosing at the right speed. In uncertain environments, the brain must continuously manage the trade-off between accuracy and reaction time: waiting longer can improve decisions, but waiting too long may reduce reward rate. How cortico-basal ganglia-thalamic (CBGT) circuits learn to tune this…
L-Dopa reshapes aperiodic brain bursts in Parkinson’s disease
Parkinson’s disease is classically associated with abnormal rhythmic activity in cortico-basal ganglia circuits, especially excessive beta-band synchronization. Yet brain activity is not made only of regular oscillations. It also contains brief, irregular, aperiodic bursts that propagate across regions and may reflect the brain’s capacity to flexibly coordinate distributed activity. In this study, in collaboration with…
What if all these different oscillations where entangled in a network of interdependence?
Linking neural activity to sensory, motor or cognitive processes is an ongoing goal in Neuroscience and articular attention has been devoted to the role of brain oscillations, analyzed by averaging over many trials in suitably designed tasks. Previous findings offer a glimpse of the complexity of the overall picture, but have also limitations. First, searching…
CBGTPy: a flexible virtual laboratory for biological decision-making
Decision-making depends on the coordinated activity of cortico-basal ganglia-thalamic circuits. These circuits help the brain evaluate alternatives, select actions, suppress inappropriate responses, and learn from reward. Yet they are difficult to study because behavior emerges from interactions between many pathways, timescales, and cell populations. CBGTPy was developed to make these interactions easier to model, manipulate,…
Mapping the energy landscape of cognition in adolescent-onset schizophrenia
Cognitive difficulties are among the most disabling aspects of schizophrenia, and they are often particularly severe in adolescent-onset schizophrenia. Yet standard neuroimaging analyses usually focus either on regional activation — which areas are more or less active — or on functional connectivity — which areas fluctuate together. In this study, in collaboration with Konasale Prasad…
Arkypallidal neurons in the external globus pallidus can mediate inhibitory control by altering competition in the striatum
Stopping an action at the right moment is a fundamental form of cognitive control. Whether avoiding an obstacle, cancelling a planned movement, or adapting to a sudden change in the environment, the brain must sometimes rapidly suppress an action that is already being prepared. This process, known as reactive inhibitory control, has classically been attributed…
Subject-specific maximum entropy model of resting state fMRI shows diagnostically distinct patterns of energy state distributions
Existing neuroimaging studies of psychotic and mood disorders have reported regional brain activation differences (first-order properties) and alterations in functional connectivity based on pairwise correlations in activation (second-order properties). In this preprint, in collaboration with Jonathan Rubin, Konasal Prasad et al. (Pittsburgh, PA), we use a generalized Ising model, also called a pairwise maximum entropy…
Different Faces of Medial Beta-Band Activity Reflect Distinct Visuomotor Feedback Signals
Beta-band activity reflects neural processes well beyond sensorimotor functions, including cognition and motivation. In this Journal of Neuroscience article in collaboration with Nicola Malfait (Marseille), by disentangling alternative spatio-temporal-spectral patterns of possible beta-oscillatory activity, we reconcile a seemingly discrepant literature. First, high-beta power in the medial frontal cortex showed opposite modulations separated in time in…
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The detail of the pattern is movement
T.S. ELIOT, from « Burnt NORTON », V (« FOUR QUARTETS », 1936—1943)
About us
The Functional System’s Dynamics team is an emergent team of the Laboratory for Cognitive and Adaptive Neuroscience (CNRS UMR 7364), within the Interdisciplinary Thematic Institute “NeuroStra” at University of Strasbourg, member of the trinational Neuroscience Upper Rhine network (NEUREX). The team was kickstarted thanks to the support of the University of Strasbourg Institute of Advanced Studies (USIAS).
How to find us
We are located within the building of the Faculty of Psychology, at the ground floor (LNCA wing, to the right, end of the corridor, entering from Rue Goethe side).
LNCA – 12 rue Goethe, F-67000 STRASBOURG
Tramway lines C/E/F – stop « Université » – Bus line 2 (~15 min from central station) – Strasbourg Entzheim airport at ~40 min, high speed train to Paris CDG and Frankfurt / Main international hubs.